Caffeine as a protective factor in dementia and Alzheimer’s disease. Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Caffeine: Cognitive and physical performance enhancer or psychoactive drug? The effect of daily caffeine use on cerebral blood flow: How much caffeine can we tolerate? Metabolic effects of caffeine in humans: Lipid oxidation or futile cycling? You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. It’s a good idea to discuss caffeine consumption with your doctor.Ĭheck out our chart about the effects of caffeine to learn more about caffeine and how it affects the body. Keep in mind that a cup is 8 ounces, and many mugs and to-go cups hold up to 16 ounces or more.Ĭaffeine tolerance and the body’s response is slightly different for each person. Safe upper levels of caffeine use during pregnancy is a bit more complicated.Ī 2020 review of studies shows that though some experts suggest that pregnant women can consume up to 300 mg per day, other studies have shown that doses of caffeine as low as 100 to 200 mg per day during pregnancy is associated with an increased risk of complications including miscarriage, fetal growth restriction, and low birth weight.įor this reason, it’s a good idea to limit caffeine intake during pregnancy and speak with your doctor for specific recommendations.Įven one cup of coffee daily can cause withdrawal symptoms. Food and Drug Administration (FDA) acknowledged that for healthy adults, up to 400 mg of caffeine in a day, or up to about four cups of coffee, was not associated with dangerous effects. There have been few randomized, controlled studies. Much of the data collected on caffeine is observational in nature.
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